Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878878 | 0.93 | LMNA (0.40) | PPARGMAPTMAPK8CCR2KMT2A | |
| SCHEMBL4871848 | 0.91 | CSNK1D (0.39) | PPARGMAPTMAPK8CCR2ROCK1 | |
| SCHEMBL4878217 | 0.90 | MAPT (0.39) | PPARGMAPTTP53THRBMAPK8 | |
| SCHEMBL4867738 | 0.89 | PTGES (0.42) | PPARGMAPTTP53THRBMAPK8 | |
| SCHEMBL4868490 | 0.89 | PPARG (0.43) | PPARGMAPTMAPK8CCR2AGTR1 | |
| SCHEMBL4868814 | 0.89 | EDNRB (0.39) | PPARGMAPTTP53THRBMAPK8 | |
| SCHEMBL4876397 | 0.87 | MAPT (0.37) | PPARGMAPTTP53THRBMAPK8 | |
| SCHEMBL4871781 | 0.86 | MAPT (0.37) | PPARGMAPTTP53THRBCCR2 | |
| SCHEMBL4868477 | 0.86 | CCR2 (0.41) | PPARGMAPTTP53CCR2AGTR1 | |
| SCHEMBL4875185 | 0.86 | PPARG (0.40) | PPARGMAPTTP53FEN1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | PPARG 2954/4885MAPT 4372/4885TP53 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.