Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31152647 | 0.89 | CALM1 (0.46) | CALM1HTR2ABCL2BCL2L1GABRA1 | |
| SCHEMBL28025161 | 0.89 | CALM1 (0.46) | CALM1HTR2ABCL2BCL2L1GABRA1 | |
| SCHEMBL3667640 | 0.87 | CALM1 (0.44) | CALM1HTR2ABCL2BCL2L1GABRA1 | |
| SCHEMBL7632934 | 0.85 | BCL2 (0.61) | CALM1HTR2ABCL2BCL2L1CTRC | |
| SCHEMBL29151966 | 0.82 | LMNA (0.43) | CALM1HTR2ABCL2BCL2L1GABRA1 | |
| SCHEMBL28806360 | 0.81 | CALM1 (0.55) | CALM1HTR2ABCL2BCL2L1CTRC | |
| SCHEMBL972711 | 0.81 | CALM1 (0.69) | CALM1HTR2ABCL2BCL2L1ALOX5 | |
| SCHEMBL29940325 | 0.80 | LIPE (0.42) | CALM1HTR2ABCL2BCL2L1CTRC | |
| SCHEMBL31596800 | 0.80 | HTR1A (0.51) | CALM1CYP3A4ALDH1A1TSHRCYP1A2 | |
| SCHEMBL28796057 | 0.80 | LIPE (0.42) | CALM1HTR2ABCL2BCL2L1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199069-A1 | POLYARYL-CONTAINING MACROCYCLIC COMPOUND AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118724916-A | Polyaryl-containing macrocyclic compounds and uses thereof | 浙江养生堂天然药物研究所有限公司 | 2024-10-01 | — | — | CN | disclosed |
| US-7314701-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2008-01-01 | — | — | US | disclosed |
| US-20050095527-A1 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-05-05 | — | — | US | disclosed |