Etifenin

Etifenin

SCHEMBL487233

CCc1cccc(CC)c1NC(=O)CN(CC(=O)O)CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ALDH1A1 P00352 3/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.54
CYP3A4 P08684 1/20 0.54
MAPK1 P28482 1/20 0.54
MC4R P32245 1/20 0.54
SCN4A P35499 1/20 0.54
MC3R P41968 1/20 0.54
HTR3A P46098 1/20 0.54
SCN5A Q14524 1/20 0.54
SCN9A Q15858 1/20 0.54
SCN3A Q9NY46 1/20 0.54
GAA P10253 1/20 0.53
BLM P54132 1/20 0.53
DRD3 P35462 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etifenin SCHEMBL10643382 0.98 ALOX15 (0.97) ALOX15TSHRCYP2C19HIF1ATDP1
Etifenin SCHEMBL10643374 0.92 ALOX15 (0.84) ALOX15TSHRCYP2C19HIF1ATDP1
SCHEMBL9318396 0.89 ALOX15 (0.81) ALOX15TSHRCYP2C19HIF1ATDP1
SCHEMBL11130240 0.87 TSHR (0.77) ALOX15TSHRCYP2C19HIF1ATDP1
SCHEMBL9972480 0.86 ALOX15 (0.76) ALOX15TSHRCYP2C19HIF1ATDP1
SCHEMBL11154960 0.83 ALOX15 (0.70) ALOX15TSHRCYP2C19HIF1ATDP1
Lidofenin SCHEMBL214472 0.82 MAPT (0.73) ALOX15TSHRCYP2C19HIF1ATDP1
SCHEMBL16520404 0.82 ALOX15 (0.68) ALOX15TSHRCYP2C19HIF1ATDP1
Lidofenin SCHEMBL28279278 0.81 MAPT (0.71) ALOX15TSHRCYP2C19HIF1ATDP1
Lidofenin SCHEMBL29765217 0.81 MAPT (0.71) ALOX15TSHRCYP2C19HIF1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
US-20230201386-A1 PRODUCING RADIOPHARMACEUTICAL COLD KITS WITHOUT LYOPHILIZATION THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2023-06-29 US claimed
CN-105572251-A Determination method of tin content in drugs JIANGSU INST NUCLEAR MEDICINE 2016-05-11 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-9000036-B2 Compositions and methods for targeting of treating neoplasms Yu, Baofa (US) 2015-04-07 US claimed
US-20140037695-A1 COMPOSITIONS AND METHODS FOR TARGETING OF TREATING NEOPLASMS YU, BAOFA 2014-02-06 US claimed
CN-103393543-A Method using 3D printing technology to prepare dropping pills WEI XUEWEN 2013-11-20 CN claimed
US-8501243-B2 Targeting cancer therapy combination YU, BAOFA 2013-08-06 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1264310-A Polymer based pharmaceutical compositions for targeted delivery of biologically active agents SDG INC (US) 2000-08-23 CN claimed
EP-1005327-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 2000-06-07 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999001110-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 1999-01-14 WO claimed
EP-0165728-B1 NMR CONTRAST AGENTS NYCOMED AS (NO) 1988-12-14 EP claimed
US-4714607-A NUCLEAR MAGNETIC RESONANCE NYCOMED AS (NO) 1987-12-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 ALOX15 414/4885TSHR 161/4885CYP2C19 1129/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 ALOX15 3077/4885TSHR 367/4885CYP2C19 3506/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG ALOX15 4533/4885TSHR 262/4885CYP2C19 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.