SCHEMBL4872798

SCHEMBL4872798

[CH2]c1ccc(CCCC)cc1O[SiH](C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.40
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
HTR1A P08908 2/20 0.38
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
RARB P10826 1/20 0.35
BIRC5 O15392 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926899 0.77 CDK1 (0.40) SKP2PPARGPPARAHTR1AHPGD
SCHEMBL8710220 0.77 SKP2 (0.37) SKP2PPARGPPARAHTR1AHPGD
SCHEMBL10893063 0.72 SKP2 (0.47) SKP2HTR1AHPGDNPC1MAPK1
SCHEMBL8893416 0.71 PPARA (0.42) PPARGPPARAHPGDNPC1RAB9A
SCHEMBL2559403 0.70 ATM (0.47) PPARGPPARANPC1MAPK1RAB9A
SCHEMBL9782927 0.70 NPC1 (0.60) SKP2PPARAHPGDNPC1MAPK1
SCHEMBL9342371 0.70 SKP2 (0.46) SKP2HPGDNPC1MAPK1HTT
SCHEMBL8704610 0.69 SKP2 (0.38) SKP2HTR1AHPGDNPC1MAPK1
SCHEMBL2759507 0.68 ATM (0.63) PPARGPPARACA2
SCHEMBL27535686 0.68 SKP2 (0.43) SKP2PPARAHTR1AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462604-B2 Hair growth promotor composition LION CORPORATION (JP) 2008-12-09 US disclosed
US-20070116657-A1 Hair growth promotor composition LION CORPORATION (JP) 2007-05-24 US disclosed
EP-1671616-A1 HAIR TONIC COMPOSITION Lion Corporation (JP) 2006-06-21 EP disclosed
EP-0540854-B1 Preparation for promoting hair growth SANSHO SEIYAKU KK (JP) 1998-01-21 EP disclosed
US-5656264-A ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE SANSYO SEIYAKU CO., LTD. (JP) 1997-08-12 US disclosed
EP-0540854-A2 Preparation for promoting hair growth Sansho Seiyaku Co., Ltd. (JP) 1993-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070116657-A1 Hair growth promotor composition BCOR, SPOUT1, IL36G SKP2 1115/4885PPARG 65/4885PPARA 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.