Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351498 | 0.85 | TSHR (0.31) | TSHR | |
| SCHEMBL10794143 | 0.78 | THRA (0.32) | TSHR | |
| SCHEMBL7529262 | 0.78 | SMN1; SMN2 (0.45) | TDP1TSHRMAPT | |
| SCHEMBL10611030 | 0.78 | TSHR (0.36) | TSHR | |
| SCHEMBL4340021 | 0.78 | LMNA (0.40) | TSHR | |
| SCHEMBL10456026 | 0.77 | TDP1 (0.56) | TDP1ERN1AKR1B1MAPTNPSR1 | |
| SCHEMBL1447962 | 0.76 | TDP1 (0.47) | TDP1ERN1AKR1B1EIF2AK2CSNK2A2 | |
| SCHEMBL30053933 | 0.76 | TDP1 (0.47) | TDP1ERN1AKR1B1EIF2AK2CSNK2A2 | |
| SCHEMBL1508459 | 0.76 | HSD17B10 (0.38) | TSHRNPSR1 | |
| SCHEMBL14343253 | 0.72 | THRB (0.36) | TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015280-A1 | Photosensitive Composition for Forming Optical Waveguide and Optical Waveguide | JSR CORPORATION (JP) | 2008-01-17 | — | — | US | disclosed |