SCHEMBL7529262

SCHEMBL7529262

C=CC(=O)OC(C)Oc1ccc(Br)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.45
LMNA P02545 5/20 0.45
ATM Q13315 2/20 0.45
HSD11B1 P28845 1/20 0.42
HPGD P15428 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPK1 P28482 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
TSHR P16473 2/20 0.36
CTSL P07711 1/20 0.35
AR P10275 1/20 0.35
ALOX15 P16050 3/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8063039 0.85 SMN1; SMN2 (0.43) SMN1; SMN2LMNAATMHSD11B1HPGD
SCHEMBL4340021 0.82 LMNA (0.40) SMN1; SMN2LMNAATMALDH1A1MEN1
SCHEMBL351498 0.81 TSHR (0.31) TSHR
SCHEMBL1508459 0.81 HSD17B10 (0.38) LMNAL3MBTL1TSHRALOX15ALOX12
SCHEMBL7520630 0.80 SMN1; SMN2 (0.45) SMN1; SMN2LMNAATMHSD11B1HPGD
SCHEMBL4758406 0.79 SMN1; SMN2 (0.38) SMN1; SMN2LMNAATMHSD11B1HPGD
SCHEMBL4872879 0.78 TDP1 (0.38) TDP1MAPTTSHR
SCHEMBL10794143 0.77 THRA (0.32) LMNATSHRAR
SCHEMBL3744533 0.77 MAPK1 (0.48) SMN1; SMN2LMNAATMHPGDNPC1
SCHEMBL2404492 0.73 LMNA (0.50) LMNARAB9AMAPK1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US claimed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US claimed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP claimed
CN-111372959-B Photopolymerizable compositions, articles, and methods comprising a urethane component and a monofunctional reactive diluent 3M创新有限公司 2022-09-02 CN disclosed
CN-114585604-A Dicarboxylic acid compound, inorganic particle treated with dicarboxylic acid compound, and composition thereof 3M创新有限公司 2022-06-03 CN disclosed
CN-113840886-A Composition comprising styrene-isoprene block copolymer and ethylenically unsaturated monomer 3M创新有限公司 2021-12-24 CN disclosed
CN-113286560-A Orthodontic articles and methods of making and post-treating the same 3M创新有限公司 2021-08-20 CN disclosed
CN-112424245-A Composition comprising styrene-isobutylene block copolymer and ethylenically unsaturated monomer 3M创新有限公司 2021-02-26 CN disclosed
CN-112367959-A Orthodontic articles comprising cured free-radically polymerizable compositions having improved strength in aqueous environments 3M创新有限公司 2021-02-12 CN disclosed
CN-111868125-A Photopolymerizable compositions, articles, and methods comprising polypropylene oxide components 3M创新有限公司 2020-10-30 CN disclosed
CN-111615377-A Orthodontic articles comprising cured free-radically polymerizable compositions containing polymers or macromolecules with photoinitiating groups 3M创新有限公司 2020-09-01 CN disclosed
CN-111372959-A Photopolymerizable compositions, articles, and methods comprising a urethane component and a monofunctional reactive diluent 3M创新有限公司 2020-07-03 CN disclosed
US-4812032-A DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE TORAY INDUSTRIES, INC. (JP) 1989-03-14 US disclosed
US-4721377-A COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE TORAY INDUSTRIES, INC. (JP) 1988-01-26 US disclosed
EP-0176874-A2 A highly-refractive plastic lens TORAY INDUSTRIES, INC. (JP) 1986-04-09 EP disclosed