SCHEMBL4874741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10016440	0.89	RAB9A (0.80)	MAPTNPC1RAB9ASMN1; SMN2KMT2A
	SCHEMBL10016416	0.83	RAB9A (1.00)	MAPTNPC1RAB9ASMN1; SMN2KMT2A
	SCHEMBL16197523	0.80	ALDH1A1 (0.81)	MAPTNPC1RAB9ASMN1; SMN2KMT2A
	SCHEMBL30778385	0.80	MAPT (0.80)	MAPTNPC1RAB9ACA12CA1
	SCHEMBL4872760	0.80	TACR1 (0.56)	MAPTNPC1RAB9ASMN1; SMN2KMT2A
	SCHEMBL15986484	0.80	CYP2C9 (0.78)	MAPTRAB9ASMN1; SMN2ALDH1A1CYP2C9
	SCHEMBL10016423	0.77	NPC1 (1.00)	MAPTNPC1RAB9ASMN1; SMN2KMT2A
	SCHEMBL4864377	0.77	PKM (0.76)	MAPTSMN1; SMN2KMT2AMEN1KDM4E
	SCHEMBL17689578	0.76	MAPT (0.77)	MAPTNPC1RAB9ASMN1; SMN2CA12
	SCHEMBL10016414	0.75	TP53 (1.00)	MAPTNPC1RAB9AUSP2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.