Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875911 | 0.91 | RXRA (0.42) | RXRARXRBRXRGFOLH1PTGER1 | |
| SCHEMBL9201143 | 0.76 | FOLH1 (0.52) | RXRARXRBRXRGFOLH1PTGER1 | |
| SCHEMBL10089235 | 0.73 | FOLH1 (0.69) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL9275556 | 0.70 | HPGD (0.46) | RXRARXRBRXRGFOLH1PTGER1 | |
| SCHEMBL28558879 | 0.70 | MRGPRX4 (0.57) | RXRARXRBRXRGFOLH1PTGER1 | |
| SCHEMBL384045 | 0.70 | RXRA (0.57) | RXRARXRBRXRGFOLH1PTGER1 | |
| SCHEMBL6762318 | 0.70 | CTSV (0.52) | RXRAFOLH1PTGER1CTSVCTSL | |
| SCHEMBL24983867 | 0.70 | FOLH1 (0.65) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL30892473 | 0.70 | FOLH1 (0.65) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL9393937 | 0.70 | FOLH1 (0.43) | RXRARXRBRXRGFOLH1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-03-20 | — | — | US | disclosed |
| US-7288273-B1 | Gallotannins and ellagitannins as regulators of cytokine release | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-10-30 | — | — | US | disclosed |
| EP-1232169-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036436-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | IL2, IL6, TNF | RXRA 4456/4885RXRB 4276/4885RXRG 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.