Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766185 | 1.00 | TRPA1 (0.52) | TRPA1TAAR1AOC3RIPK1CYP2D6 | |
| SCHEMBL8207431 | 0.83 | TRPA1 (0.41) | TRPA1TAAR1 | |
| SCHEMBL19101811 | 0.80 | TAAR1 (0.50) | TRPA1TAAR1AOC3RIPK1 | |
| SCHEMBL19101722 | 0.80 | TAAR1 (0.50) | TRPA1TAAR1AOC3RIPK1 | |
| SCHEMBL28874660 | 0.80 | TSHR (0.38) | TRPA1TAAR1CYP2D6CAPN1 | |
| SCHEMBL3672929 | 0.79 | TRPA1 (0.67) | TRPA1TAAR1AOC3RIPK1 | |
| SCHEMBL22092210 | 0.76 | TRPA1 (0.53) | TRPA1TAAR1 | |
| SCHEMBL7041592 | 0.76 | TRPA1 (0.57) | TRPA1TAAR1AOC3RIPK1 | |
| SCHEMBL508412 | 0.75 | TRPA1 (0.61) | TRPA1TAAR1AOC3RIPK1 | |
| SCHEMBL9579271 | 0.75 | TRPA1 (0.61) | TRPA1TAAR1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63166853-A | — | — | None | — | — | JP | disclosed |
| JP-63183522-A | — | — | None | — | — | JP | disclosed |
| US-9856196-B2 | Agent for reduction of sensory irritation | KAO CORPORATION (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20140323586-A1 | Agent for Reduction of Sensory Irritation | KAO CORPORATION (JP) | 2014-10-30 | — | — | US | disclosed |
| US-20140323586-A1 | Agent for Reduction of Sensory Irritation | KAO CORPORATION (JP) | 2014-10-30 | — | — | US | disclosed |
| US-8754107-B2 | Aminopyrrolidines as chemokine receptor antagonists | ABBVIE INC. (US) | 2014-06-17 | — | — | US | disclosed |
| WO-2013103155-A1 | AGENT FOR REDUCTION OF SENSORY IRRITATION | KAO CORPORATION (JP) | 2013-07-11 | — | — | WO | disclosed |
| US-20080176883-A1 | Antiinflammtory, antiproliferative, anticancer agents; (3-Hydroxy-pyrrolidin-1-yl)-(3-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone | ABBVIE INC. | 2008-07-24 | — | — | US | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| US-4837351-A | FRUITS, FLOWERS | KURARAY COMPANY LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| JP-S63183522-A | PERFUME COMPOSITION | KURARAY CO LTD | 1988-07-28 | — | — | JP | disclosed |
| EP-0275434-A1 | 2-Cyano-4-phenyl pentane and fragrance or perfume compositions containing the same | KURARAY CO., LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |
| JP-S63166853-A | 2-CYANO-4-PHENYLPENTANE AND PERFUMERY COMPOSITION CONTAINING THE SAME | KURARAY CO LTD | 1988-07-11 | — | — | JP | disclosed |
| US-4650898-A | PERFUMES, FOODS, CHEWING GUMS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1987-03-17 | — | — | US | disclosed |
| US-4610812-A | Uses of methyl phenyl pentanol derivatives in augmenting or enhancing the aroma or taste of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176883-A1 | Antiinflammtory, antiproliferative, anticancer agents; (3-Hydroxy-pyrrolidin-1-yl)-(3-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone | MIF, CCL5, CCR2 | TRPA1 657/4885TAAR1 231/4885AOC3 2577/4885 |
| US-20140323586-A1 | Agent for Reduction of Sensory Irritation | TRPA1, TRPV1, TRPV2 | TRPA1 1/4885TAAR1 110/4885AOC3 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.