Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487368 | 0.79 | HCAR2 (0.50) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL30792836 | 0.79 | HCAR2 (0.50) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL2126833 | 0.78 | TPMT (0.50) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL30908604 | 0.76 | HCAR2 (0.47) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL31700802 | 0.76 | HCAR2 (0.47) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL4897370 | 0.76 | HCAR2 (0.47) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL31386903 | 0.76 | GABRP (0.52) | HCAR2POLBMGAMP4HA1P4HTM | |
| SCHEMBL836470 | 0.76 | TPMT (0.48) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL10200753 | 0.76 | TPMT (0.48) | TPMTHCAR2POLBMGAMP4HA1 | |
| SCHEMBL487373 | 0.76 | HCAR2 (0.47) | TPMTHCAR2POLBMGAMP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049488-B1 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-09 | — | — | EP | disclosed |
| EP-2004636-B1 | Substituted enaminocarbonyl compounds used as insecticides | BAYER IP GMBH (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| EP-2707373-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | Bayer Intellectual Property GmbH (DE) | 2014-03-19 | — | — | EP | disclosed |
| CN-101460502-B | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG | 2013-07-17 | — | — | CN | disclosed |
| EP-2021344-B1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| EP-2004606-B1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2012152741-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-15 | — | — | WO | disclosed |
| CN-101454316-B | Substituted enaminocarbonyl compounds for use as pesticides | BAYER CROPSCIENCE AG | 2012-08-15 | — | — | CN | disclosed |
| US-8138350-B2 | N′-cyano-N-halogenalkylimidamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| CN-101454316-A | Substituted enaminocarbonyl compounds for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-10 | — | — | CN | disclosed |
| EP-2049488-A2 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2009-04-22 | — | — | EP | disclosed |
| CN-101415682-A | Substituted enaminocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2009-04-22 | — | — | CN | disclosed |
| EP-2021344-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | Bayer CropScience AG (DE) | 2009-02-11 | — | — | EP | disclosed |
| EP-2004606-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | Bayer CropScience AG (DE) | 2008-12-24 | — | — | EP | disclosed |
| EP-2004636-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | Bayer CropScience AG (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008009360-A2 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007115643-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115646-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007115647-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BROX, BOLA2; BOLA2B, CAT | TPMT 63/4885HCAR2 4183/4885POLB 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.