Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.42 |
| ▸ | MLYCD | O95822 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422948 | 0.86 | MLYCD (0.43) | MEN1KMT2ANR1H2NR1H3MLYCD | |
| SCHEMBL4424260 | 0.81 | PLAU (0.41) | MEN1KMT2A | |
| SCHEMBL4417912 | 0.69 | EGLN1 (0.46) | MEN1KMT2AMLYCDRORCPGR | |
| SCHEMBL4879317 | 0.69 | EGLN1 (0.43) | KMT2ANR1H2NR1H3MLYCD | |
| SCHEMBL4430547 | 0.69 | MLYCD (0.41) | MEN1KMT2ANR1H2NR1H3MLYCD | |
| SCHEMBL7371125 | 0.67 | S1PR1 (0.48) | MEN1KMT2AS1PR1CYP11B1CYP11B2 | |
| SCHEMBL4882528 | 0.67 | TLR8 (0.43) | NR1H2NR1H3MLYCDRORCPGR | |
| SCHEMBL27194609 | 0.67 | MEN1 (0.51) | MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL30885547 | 0.67 | MEN1 (0.51) | MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8007698 | 0.66 | ESR1 (0.50) | KMT2ATEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070869-A1 | Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-03-20 | — | — | US | claimed |
| US-7279477-B2 | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-10-09 | — | — | US | claimed |
| US-20040063671-A1 | Malonyl-coa decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-04-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063671-A1 | Malonyl-coa decarboxylase inhibitors useful as metabolic modulators | MLYCD, ACACA, ME1 | MEN1 1075/4885KMT2A 1299/4885NR1H2 1305/4885 |
| US-20080070869-A1 | Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators | MLYCD, ME3, ACACA | MEN1 1149/4885KMT2A 1243/4885NR1H2 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.