Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 15/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877467 | 0.79 | HCAR2 (0.53) | HCAR2KMT2A | |
| SCHEMBL4877565 | 0.78 | KDM4E (0.46) | HCAR2KMT2A | |
| SCHEMBL22637676 | 0.77 | HCAR2 (0.52) | HCAR2HCAR3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4631308 | 0.71 | HCAR2 (0.63) | HCAR2 | |
| SCHEMBL7234538 | 0.70 | HCAR2 (0.57) | HCAR2HCAR3KMT2A | |
| SCHEMBL31741716 | 0.68 | HCAR2 (0.59) | HCAR2KMT2A | |
| SCHEMBL15859525 | 0.68 | HCAR2 (0.55) | HCAR2KMT2A | |
| SCHEMBL17065994 | 0.68 | HCAR2 (0.55) | HCAR2KMT2A | |
| SCHEMBL12263262 | 0.68 | HCAR2 (0.55) | HCAR2KMT2A | |
| SCHEMBL29956356 | 0.67 | HCAR2 (0.53) | HCAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090836-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | BIOLIPOX AB (SE) | 2008-04-17 | — | — | US | disclosed |
| EP-1794130-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006032852-A1 | PYRAZOLE COMPOUNDS USEFUL UIN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090836-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | ALOX15, ALOX15B, ALOX12 | HCAR2 336/4885HCAR3 393/4885PRKAB2 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.