Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 17/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4873602 | 0.98 | PRSS1 (0.55) | PRSS1PLAUF12F2PLG | |
| SCHEMBL7330212 | 0.87 | PRSS1 (0.49) | PRSS1PLAU | |
| SCHEMBL9314470 | 0.81 | LMNA (0.54) | PRSS1PLAULMNAF12MASP2 | |
| SCHEMBL1303895 | 0.81 | PRSS1 (0.57) | PRSS1PLAUMASP2THPOF2 | |
| SCHEMBL8065481 | 0.80 | ALDH1A1 (0.50) | PRSS1LMNA | |
| Hydrochloric Acid SCHEMBL4280302 | 0.79 | LMNA (0.52) | PRSS1PLAULMNAF12MASP2 | |
| Hydrochloric Acid SCHEMBL30833530 | 0.79 | PRSS1 (0.58) | PRSS1PLAUMASP2THPOF2 | |
| Hydrochloric Acid SCHEMBL8412855 | 0.79 | PRSS1 (0.58) | PRSS1PLAUMASP2THPOF2 | |
| Hydrochloric Acid SCHEMBL1303376 | 0.79 | PRSS1 (0.58) | PRSS1PLAUMASP2THPOF2 | |
| SCHEMBL3015286 | 0.77 | LCK (0.55) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051388-A1 | Novel Compounds That Inhibit Factor Xa Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2008-02-28 | — | — | US | disclosed |
| EP-1470143-B1 | COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY | MORPHOCHEM AG KOMB CHEMIE (DE) | 2007-10-31 | — | — | EP | disclosed |
| CN-1322001-C | Novel compounds that inhibit factor Xa activity | MORPHOCHEM AG FUER KOM (DE) | 2007-06-20 | — | — | CN | disclosed |
| EP-1773855-A1 | NOVEL COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008141-A1 | NOVEL COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2006-01-26 | — | — | WO | disclosed |
| CN-1625559-A | Novel compounds that inhibit factor Xa activity | MORPHOCHEM AG FUER KOM (DE) | 2005-06-08 | — | — | CN | disclosed |
| US-20050049283-A1 | Compounds that inhibit factor xa activity | MORPHOCHEM AKTIENGESELLSHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2005-03-03 | — | — | US | disclosed |
| EP-1470143-A1 | COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064440-A1 | COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051388-A1 | Novel Compounds That Inhibit Factor Xa Activity | SERPINC1, TFPI, F11 | PRSS1 40/4885PLAU 28/4885LMNA 939/4885 |
| US-20050049283-A1 | Compounds that inhibit factor xa activity | F11, TFPI, SERPINC1 | PRSS1 83/4885PLAU 39/4885LMNA 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.