Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172529 | 0.86 | BRD4 (0.35) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL4180098 | 0.82 | DDB1 (0.37) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL4135830 | 0.77 | KDM4E (0.42) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL4135833 | 0.77 | KDM4E (0.42) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL4175922 | 0.76 | KDM4E (0.42) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL4887129 | 0.76 | KDM4E (0.44) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL4178090 | 0.75 | SIGMAR1 (0.37) | ALDH1A1L3MBTL1BRD4MEN1KMT2A | |
| SCHEMBL4178092 | 0.74 | SIGMAR1 (0.35) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL3816675 | 0.73 | LMNA (0.55) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3981476 | 0.73 | MTNR1A (0.42) | ALDH1A1KDM4EMAPTMAPK1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | GLAXO GROUP LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | MRPL21, MRPS18A, MRPL19 | ALDH1A1 3772/4885HPGD 2304/4885HSD17B10 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.