Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765410 | 0.80 | HTR2C (0.51) | HTR2CHTR2AHTR2BSLC6A4ADRB2 | |
| SCHEMBL10700915 | 0.79 | KCNA5 (0.50) | ALDH1A1KCNA5LMNA | |
| SCHEMBL7540738 | 0.76 | KDM1A (0.49) | SLC6A4ALDH1A1KCNA5DRD2LMNA | |
| SCHEMBL27765409 | 0.75 | HTR2C (0.51) | HTR2CHTR2AHTR2BSLC6A4ADRB2 | |
| SCHEMBL10715246 | 0.75 | TRPM8 (0.44) | ALDH1A1KCNA5LMNA | |
| SCHEMBL8498802 | 0.74 | KCNA5 (0.46) | HTR2CHTR2AHTR2BALDH1A1KCNA5 | |
| SCHEMBL5824341 | 0.73 | OPRM1 (0.47) | HTR2CHTR2AHTR2BALDH1A1KCNA5 | |
| SCHEMBL4631746 | 0.73 | KCNA5 (0.41) | ALDH1A1KCNA5LMNA | |
| SCHEMBL8336802 | 0.73 | KCNA5 (0.44) | ALDH1A1KCNA5LMNA | |
| SCHEMBL11858717 | 0.72 | KCNA5 (0.39) | ALDH1A1KCNA5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | claimed |
| US-8658231-B2 | Coffee flavour modification process | KRAFT FOODS R&D, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20080299283-A1 | COFFEE FLAVOUR MODIFICATION PROCESS | INTERCONTINENTAL GREAT BRANDS LLC | 2008-12-04 | — | — | US | disclosed |
| EP-1872665-A1 | Coffee flavour modification process | Kraft Foods R & D, Inc. Zweigniederlassung München (DE) | 2008-01-02 | — | — | EP | disclosed |
| US-6147051-A | ANTIISCHEMIC AGENT | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |