Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241398 | 0.87 | S1PR1 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL25246406 | 0.86 | S1PR1 (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28506967 | 0.83 | GRIN2D (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL633379 | 0.80 | PGK1 (0.55) | ALDH1A1TDP1ENPP2PGK1PGK2 | |
| SCHEMBL1226280 | 0.77 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL50012 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1THRATHRB | |
| SCHEMBL1647493 | 0.76 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1THRATHRB | |
| SCHEMBL328799 | 0.76 | FDPS (0.45) | ALDH1A1TDP1PGK1PGK2 | |
| SCHEMBL2199110 | 0.75 | ESR1 (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL978688 | 0.74 | PPARD (0.39) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114128-A1 | Synthesis of Copolymers in the Form of a Mikto Star by Controlled Radical Polymerization | RHODIA CHIMIE (FR) | 2008-05-15 | — | — | US | claimed |
| US-20080114128-A1 | Synthesis of Copolymers in the Form of a Mikto Star by Controlled Radical Polymerization | RHODIA CHIMIE (FR) | 2008-05-15 | — | — | US | disclosed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | disclosed |
| US-6900251-B2 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2005-05-31 | — | — | US | disclosed |
| EP-1148071-B1 | Hydrolysis-stable and polymerisable acrylphosphonic acid mono esters | IVOCLAR VIVADENT AG (LI) | 2004-06-16 | — | — | EP | disclosed |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | disclosed |
| US-6710149-B2 | USE OF ACRYLOPHOSPHONIC ACID AS A COMPONENT OF AN ADHESIVE, OF A POLYMER, OF A COMPOSITE, OF A CEMENT, OF A MOLDED ARTICLE AND IN PARTICULAR OF A DENTAL MATERIAL | IVOCLAR VIVADENT AG (LI) | 2004-03-23 | — | — | US | disclosed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | disclosed |
| EP-1148060-B1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2003-09-10 | — | — | EP | disclosed |
| EP-0909761-B1 | Hydrolysis-stable and polymerizable acryl phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2003-04-02 | — | — | EP | disclosed |
| US-6350839-B2 | THE MONOESTER OF THE PHOSPHONIC ACID GROUP ALSO HAS IMPROVED SOLUBILITY IN POLAR ORGANIC SOLVENTS, AND WATER THAN THE CORRESPONDING ACID; USE IN DENTISTRY | IVOCLAR VIVADENT AG (LI) | 2002-02-26 | — | — | US | disclosed |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | IVOCLAR VIVADENT AG. | 2002-02-07 | — | — | US | disclosed |
| US-20010044513-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid monoesters | IVOCLAR VIVADENT AG | 2001-11-22 | — | — | US | disclosed |
| EP-1148060-A1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
| EP-1148071-A2 | Hydrolysis-stable and polymerisable acrylphosphonic acid mono esters | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
| US-6172131-B1 | MADE BY REACTING AN ALPHA-HALOMETHACRYLIC ACID ESTER WITH PROTECTED MONO- OR DIFUNCTIONAL PHOSPHONIC ACID ESTERS; USE AS COMPONENT OF DENTAL ADHESIVES DUE TO THEIR ADHESION-PROMOTING PROPERTIES | IVOCLAR AG | 2001-01-09 | — | — | US | disclosed |
| EP-0909761-A1 | Hydrolysis-stable and polymerizable acryl phosphonic acids | IVOCLAR AG (LI) | 1999-04-21 | — | — | EP | disclosed |
| US-5124047-A | Allylphosphonate copolymer, in aqueous systems | W. R. GRACE & CO.-CONN. (US) | 1992-06-23 | — | — | US | disclosed |
| US-5091491-A | Water-soluble allylphosphonate copolymers | W. R. GRACE & CO.-CONN. (US) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | PHOSPHO1, RER1, PTGER1 | GRIN2D 575/4885GRIN3B 1008/4885GRIN1 107/4885 |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | PHOSPHO1, PPA1, ABHD16A | GRIN2D 1792/4885GRIN3B 1612/4885GRIN1 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.