Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794147 | 0.91 | PTGIR (0.40) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4793947 | 0.86 | ADRA2A (0.40) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4795011 | 0.85 | PTGIR (0.38) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4795892 | 0.84 | ADRA2A (0.41) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4795965 | 0.84 | ADRA2A (0.41) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4878946 | 0.84 | ADRA2A (0.39) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4795959 | 0.82 | ADRA2A (0.39) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4792540 | 0.80 | ADRA2A (0.43) | PTGIRADRA2AADRA2BADRA2CAOC3 | |
| SCHEMBL4774672 | 0.78 | NOS3 (0.43) | MEN1KMT2A | |
| SCHEMBL4792493 | 0.77 | PTH1R (0.42) | PTGIRADRA2AADRA2BADRA2CAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |