Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774626 | 0.88 | NOS3 (0.43) | NOS3NOS1NOS2HRH2HRH3 | |
| SCHEMBL4774611 | 0.84 | LTB4R (0.47) | LTB4RMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4776700 | 0.82 | HRH2 (0.42) | NOS3NOS1NOS2HRH2HRH3 | |
| SCHEMBL4776778 | 0.80 | NFE2L2 (0.44) | NOS3NOS1NOS2LTB4RMEN1 | |
| SCHEMBL4881501 | 0.78 | PTGIR (0.40) | MEN1KMT2A | |
| SCHEMBL4776697 | 0.76 | HRH2 (0.37) | NOS3NOS1NOS2HRH2HRH3 | |
| SCHEMBL4776218 | 0.73 | CYP19A1 (0.42) | LTB4RMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4778112 | 0.72 | NOS3 (0.47) | NOS3NOS1NOS2LTB4RMEN1 | |
| Benzidine SCHEMBL28120863 | 0.70 | MAOB (0.64) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL20547931 | 0.70 | LTB4R (0.55) | LTB4RTLR8MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |