Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134106 | 0.92 | CHRNA7 (0.47) | RIPK1NPY5RS1PR4 | |
| SCHEMBL9133124 | 0.82 | BAZ2B (0.59) | RIPK1NPY5RMAPTSMN1; SMN2POLB | |
| SCHEMBL9133647 | 0.76 | AURKA (0.57) | RIPK1MAPTSMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL9133303 | 0.75 | BAZ2B (0.54) | NPC1RAB9AS1PR4 | |
| SCHEMBL9133111 | 0.74 | MAPT (0.41) | RIPK1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14825173 | 0.73 | POLB (0.56) | MAPTSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL9134544 | 0.72 | KMT2A (0.49) | RIPK1MAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL26849762 | 0.72 | RAB9A (0.56) | RIPK1MAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL9134113 | 0.71 | ENPP3 (0.39) | NPY5RMAPTPOLBNPC1RAB9A | |
| SCHEMBL9510816 | 0.70 | MAPT (0.63) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090836-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | BIOLIPOX AB (SE) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090836-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | ALOX15, ALOX15B, ALOX12 | RIPK1 1378/4885NPY5R 189/4885MAPT 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.