Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.64 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.63 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294334 | 0.84 | SLC6A12 (0.61) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL31736417 | 0.84 | MCHR1 (0.77) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL2233466 | 0.83 | KCNH2 (0.80) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL694949 | 0.83 | SIGMAR1 (0.82) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL4894227 | 0.83 | MCHR1 (0.79) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL61848 | 0.80 | TMEM97 (0.83) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL4883868 | 0.79 | PRKAA2 (0.61) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL7218186 | 0.78 | DRD4 (0.86) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 | |
| SCHEMBL8706202 | 0.78 | DRD4 (0.87) | SLC6A12SLC6A13DRD4SIGMAR1TMEM97 | |
| SCHEMBL17946338 | 0.78 | KMT2A (0.80) | SLC6A12SLC6A13KCNH2DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| EP-1761526-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005118579-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | SLC6A12 2262/4885SLC6A13 2339/4885KCNH2 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.