Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RGS4 | P49798 | 6/20 | 0.37 |
| ▸ | RGS8 | P57771 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882281 | 0.71 | ALDH1A1 (0.44) | ALDH1A1RGS4RGS8GSK3BPOLB | |
| SCHEMBL4874761 | 0.68 | ALDH1A1 (0.80) | ALDH1A1POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL27660999 | 0.60 | ALDH1A1 (0.40) | ALDH1A1POLBTDP1L3MBTL1TSHR | |
| SCHEMBL838929 | 0.60 | RGS4 (0.58) | RGS4RGS8GSK3BTDP1L3MBTL1 | |
| SCHEMBL7038437 | 0.59 | ALDH1A1 (0.46) | ALDH1A1POLBTSHRKDM4EMEN1 | |
| SCHEMBL8434025 | 0.59 | PTGS2 (0.48) | RGS4RGS8GSK3BTDP1L3MBTL1 | |
| SCHEMBL24031478 | 0.56 | RGS4 (0.54) | RGS4RGS8GSK3BTDP1L3MBTL1 | |
| SCHEMBL4883169 | 0.56 | TSHR (0.50) | ALDH1A1RGS4RGS8POLBTDP1 | |
| SCHEMBL7806764 | 0.55 | TSHR (0.40) | ALDH1A1RGS4POLBTDP1L3MBTL1 | |
| SCHEMBL9473364 | 0.55 | MAPT (0.47) | ALDH1A1RGS4RGS8GSK3BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | IMMUSOL INCORPORATED (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | NQO2, MCL1, KRAS | ALDH1A1 3206/4885RGS4 691/4885RGS8 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.