Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883211 | 1.00 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4887969 | 1.00 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4887975 | 1.00 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5715915 | 0.91 | NPC1 (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5715919 | 0.91 | NPC1 (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4888888 | 0.88 | CYP1A2 (0.64) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4888895 | 0.88 | CYP1A2 (0.64) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4883238 | 0.87 | ALDH1A1 (0.54) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4883234 | 0.87 | ALDH1A1 (0.54) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4878016 | 0.86 | NPC1 (0.59) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | KMT2A 3684/4885MEN1 4240/4885RAB9A 3811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.