SCHEMBL4883418

SCHEMBL4883418

O=C1NS(=O)(=S)c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 6/20 0.67
CA12 O43570 5/20 0.67
CA2 P00918 5/20 0.67
CA1 P00915 3/20 0.67
CA4 P22748 3/20 0.67
CA7 P43166 3/20 0.67
KMT2A Q03164 2/20 0.67
KDM4E B2RXH2 1/20 0.67
USP2 O75604 1/20 0.67
LMNA P02545 1/20 0.67
BCHE P06276 1/20 0.67
CA6 P23280 1/20 0.67
CA5A P35218 1/20 0.67
CA14 Q9ULX7 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
PDE7A Q13946 1/20 0.48
PDE7B Q9NP56 1/20 0.48
GPR3 P46089 1/20 0.44
ALDH1A1 P00352 2/20 0.43
GSK3B P49841 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL3816 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL4199164 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL588640 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL4777123 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL6049140 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL29358404 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL29191365 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL7073018 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL6033672 0.80 CA12 (1.00) CA9CA12CA2CA1CA4
Saccharin SCHEMBL2526712 0.78 CA12 (0.96) CA9CA12CA2CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287032-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME LLC (US) 2023-09-14 US claimed
EP-4196131-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES Merck Sharp & Dohme LLC (US) 2023-06-21 EP claimed
WO-2022035917-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME CORP. (US) 2022-02-17 WO claimed
EP-0403366-B1 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT ENERGIE ATOMIQUE (FR) 1995-02-22 EP claimed
EP-0403366-A2 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-12-19 EP claimed
JP-6211888-A None JP disclosed
US-12422394-B2 Devices and methods including a preconcentrator material for detection of analytes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-09-23 US disclosed
US-20240274855-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-08-15 US disclosed
US-20230287032-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME LLC (US) 2023-09-14 US disclosed
EP-4196131-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES Merck Sharp & Dohme LLC (US) 2023-06-21 EP disclosed
EP-2606529-B1 ELECTROCHEMICAL CELL MASSACHUSETTS INST TECHNOLOGY (US) 2022-11-23 EP disclosed
US-20220057352-A1 DEVICES AND METHODS INCLUDING A PRECONCENTRATOR MATERIAL FOR DETECTION OF ANALYTES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-02-24 US disclosed
US-5736533-A INHIBITING COLONIZATION OF STREPTOCOCCUS PNEUMONIAE, HEMOPHILUS INFLUENZA OR PARAINFLUENZA, BURKHOLDERIA (PSEUDOMONAS) CEPACIA BY ADMINISTERING BINDING INHIBITING OLIGOSACCHARIDE NEOSE TECHNOLOGIES, INC. (US) 1998-04-07 US disclosed
WO-1996040169-A1 BACTERIAL INHIBITION WITH AN OLIGOSACCHARIDE COMPOUND NEOSE TECHNOLOGIES, INC. (US) 1996-12-19 WO disclosed
EP-0403366-B1 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT ENERGIE ATOMIQUE (FR) 1995-02-22 EP disclosed
JP-H06211888-A NEW 16-MEMBERED RING MACROLIDE DERIVATIVE AND ITS PRODUCTION MEIJI SEIKA KAISHA LTD 1994-08-02 JP disclosed
EP-0403366-A2 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-12-19 EP disclosed
EP-0337229-A2 Substituted pyri(mi)dines BAYER AG (DE) 1989-10-18 EP disclosed
EP-0327913-A2 Substituted azolyl methyl oxiranes BAYER AG (DE) 1989-08-16 EP disclosed
EP-0327899-A2 Substituted vinyl azoles BAYER AG (DE) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287032-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES NUDT1, NT5C3B, DUT CA9 3944/4885CA12 4864/4885CA2 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.