Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232694 | 0.85 | CYP1A2 (0.39) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30946339 | 0.85 | CYP1A2 (0.39) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30733977 | 0.76 | DGAT1 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL564729 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3633773 | 0.70 | P2RX7 (0.40) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28349851 | 0.68 | NQO2 (0.31) | — | |
| SCHEMBL29505874 | 0.68 | NQO2 (0.31) | — | |
| SCHEMBL22234567 | 0.68 | PIM1 (0.43) | KDM4ETSHRTGFBR1TDP1SCN9A | |
| SCHEMBL29444559 | 0.68 | PIM1 (0.43) | KDM4ETSHRTGFBR1TDP1SCN9A | |
| SCHEMBL9690501 | 0.68 | GABRP (0.39) | KDM4EALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101677549-A | Use of pyridine-2-oxy-3-carboxamides as safeners | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | disclosed |
| WO-2008131861-A1 | USE OF PYRIDINE-2-OXY-3-CARBONAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | KDM4E 3015/4885ALDH1A1 279/4885MAPT 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.