Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632864 | 0.86 | CASP1 (0.36) | PARP1LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL4480620 | 0.85 | TAS2R14 (0.46) | P2RX7LMNAGAATUBB4ATUBB | |
| SCHEMBL4191868 | 0.81 | IKBKB (0.42) | P2RX7PARP1JAK2LMNAGAA | |
| SCHEMBL3453722 | 0.80 | CASP1 (0.43) | P2RX7PARP1JAK2LMNAGAA | |
| SCHEMBL30489817 | 0.80 | CASP1 (0.43) | P2RX7PARP1JAK2LMNAGAA | |
| SCHEMBL3550940 | 0.80 | LMNA (0.54) | P2RX7LMNAGAANPC1RAB9A | |
| SCHEMBL30572236 | 0.80 | LMNA (0.54) | P2RX7LMNAGAANPC1RAB9A | |
| SCHEMBL15547246 | 0.77 | TUBB4A (0.42) | P2RX7LMNAGAATUBB4ATUBB | |
| SCHEMBL9264129 | 0.77 | TUBB4A (0.54) | LMNAGAATUBB4ATUBBTUBA3C | |
| SCHEMBL12775473 | 0.77 | LMNA (0.42) | P2RX7PARP1JAK2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959863-B | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2014-01-08 | — | — | CN | claimed |
| CN-101959863-A | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2011-01-26 | — | — | CN | claimed |
| EP-2251329-A1 | PROCESS FOR PRODUCTION OF 3-AMINO-2-CHLORO-6- TRIFLUOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-17 | — | — | EP | claimed |
| WO-2020245088-A1 | ADJUVANT COMBINATIONS AS FOLIAR UPTAKE ACCELERATORS FOR HERBICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-10 | — | — | WO | disclosed |
| CN-101959863-B | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2014-01-08 | — | — | CN | disclosed |
| CN-101959863-B | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2014-01-08 | — | — | CN | disclosed |
| US-8293900-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293900-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP (US) | 2012-10-23 | — | — | US | disclosed |
| CN-101959863-A | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2011-01-26 | — | — | CN | disclosed |
| CN-101959863-A | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2011-01-26 | — | — | CN | disclosed |
| EP-2251329-A1 | PROCESS FOR PRODUCTION OF 3-AMINO-2-CHLORO-6- TRIFLUOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-17 | — | — | EP | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20070265164-A1 | Active Substances for Increasing Pathogenic Defense in Plants and Methods for the Detection Thereof | BAYER CROPSCIENCE GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-20070265164-A1 | Active Substances for Increasing Pathogenic Defense in Plants and Methods for the Detection Thereof | BAYER CROPSCIENCE GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| WO-2007041052-A2 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | P2RX7 1542/4885PARP1 1761/4885JAK2 3734/4885 |
| US-20070265164-A1 | Active Substances for Increasing Pathogenic Defense in Plants and Methods for the Detection Thereof | ME1, GUSB, CHI3L1 | P2RX7 3822/4885PARP1 3808/4885JAK2 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.