Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102109 | 0.85 | TP53 (0.47) | TP53L3MBTL1SMN1; SMN2TSHRACHE | |
| SCHEMBL8827906 | 0.85 | ALDH1A1 (0.39) | TP53L3MBTL1SMN1; SMN2TSHRACHE | |
| SCHEMBL7275212 | 0.84 | SIGMAR1 (0.45) | L3MBTL1SMN1; SMN2TSHRMAPTNPSR1 | |
| SCHEMBL10874214 | 0.84 | TDP1 (0.38) | TP53TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL10567035 | 0.83 | SIGMAR1 (0.43) | TP53TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9249991 | 0.83 | CACNA1B (0.45) | L3MBTL1SMN1; SMN2MAPTALDH1A1ADORA3 | |
| SCHEMBL7326485 | 0.83 | CACNA1B (0.45) | L3MBTL1SMN1; SMN2MAPTALDH1A1ADORA3 | |
| SCHEMBL10872894 | 0.83 | TDP1 (0.38) | TP53TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL7429615 | 0.82 | TDP1 (0.37) | TP53TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL7365756 | 0.81 | CACNA1B (0.40) | TP53MAPTNPSR1ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63041459-A | — | — | None | — | — | JP | disclosed |
| US-20080095841-A1 | Pharmaceutical Composition, Method for Producing the Same, and Method for Stabilizing Dihydropyridine Compound in the Pharmaceutical Composition | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1813274-A1 | MEDICINAL COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND METHOD OF STABILIZING DIHYDROPYRIDINE COMPOUND IN MEDICINAL COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
| JP-S6341459-A | PRODUCTION OF 2-(N-BENZYL-N-METHYLAMINO)- ETHYLMETHYL-2, 6-DIMETHYL-4-(M-NITROPHENYL)-1, 4-DIHYDROPYRIDINE-3, 5-DICARBOXYLATE AND HYDROCHLORIDE THEREOF | LEK TOVARNA FARMACEVTSKIH | 1988-02-22 | — | — | JP | disclosed |