Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267935 | 0.84 | LMNA (0.44) | SIGMAR1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL4883866 | 0.84 | TP53 (0.43) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL4883921 | 0.84 | LMNA (0.45) | SIGMAR1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8827906 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2ALMNACYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL4885075 | 0.82 | ADRA1A (0.52) | SIGMAR1KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL9102109 | 0.79 | TP53 (0.47) | ALDH1A1LMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL9249991 | 0.79 | CACNA1B (0.45) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7326485 | 0.79 | CACNA1B (0.45) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7289949 | 0.79 | MEN1 (0.41) | ALDH1A1KMT2AMEN1HPGDRAB9A | |
| SCHEMBL7284574 | 0.77 | ADRB1 (0.46) | ALDH1A1KMT2AMEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |