Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874214 | 0.84 | TDP1 (0.38) | TDP1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL10872894 | 0.83 | TDP1 (0.38) | TDP1ALDH1A1LMNAKMT2ATP53 | |
| SCHEMBL4883866 | 0.82 | TP53 (0.43) | TDP1ALDH1A1LMNAKMT2ATP53 | |
| SCHEMBL4756165 | 0.79 | TP53 (0.43) | TDP1ALDH1A1LMNAKMT2ATP53 | |
| SCHEMBL10567035 | 0.78 | SIGMAR1 (0.43) | TDP1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL8295139 | 0.77 | ALDH1A1 (0.39) | TDP1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL3392997 | 0.76 | TDP1 (0.40) | TDP1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL7439133 | 0.75 | TDP1 (0.38) | TDP1ALDH1A1LMNAKMT2ATP53 | |
| SCHEMBL8827906 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EKMT2ATP53 | |
| SCHEMBL4758254 | 0.74 | HCAR3 (0.39) | TDP1ALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | disclosed |
| US-4145432-A | 6-ACYLORYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND A METHOD OF EFFECTING VASODILATION THEREWITH | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |