Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249991 | 1.00 | CACNA1B (0.45) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL7365756 | 0.93 | CACNA1B (0.40) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL7366816 | 0.89 | CACNA1B (0.39) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL9830227 | 0.88 | HTT (0.47) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL7283842 | 0.85 | MEN1 (0.38) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL4883866 | 0.83 | TP53 (0.43) | ALDH1A1MEN1ADORA3KMT2ACACNA1C | |
| SCHEMBL7284284 | 0.82 | CACNA1B (0.37) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL9831502 | 0.82 | MAOB (0.40) | CACNA1BNFE2L2HTTALDH1A1MEN1 | |
| SCHEMBL8827906 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL7275212 | 0.79 | SIGMAR1 (0.45) | HTTALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |