Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CCR8 | P51685 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881599 | 0.85 | L3MBTL1 (0.60) | L3MBTL1SIGMAR1ALDH1A1CCR8LMNA | |
| SCHEMBL4878355 | 0.85 | SIGMAR1 (0.60) | L3MBTL1SIGMAR1ALDH1A1CCR8LMNA | |
| SCHEMBL4880538 | 0.85 | SOAT1 (0.50) | MMP9MMP13ALDH1A1 | |
| SCHEMBL4881139 | 0.84 | OPRD1 (0.47) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL2701083 | 0.83 | SIGMAR1 (0.57) | L3MBTL1SIGMAR1ALDH1A1CCR8LMNA | |
| SCHEMBL4883886 | 0.82 | L3MBTL1 (0.54) | MMP1MMP9MMP13ADAM17L3MBTL1 | |
| SCHEMBL8349894 | 0.81 | SIGMAR1 (0.55) | L3MBTL1SIGMAR1ALDH1A1CCR8LMNA | |
| SCHEMBL4876705 | 0.81 | OPRD1 (0.46) | ALDH1A1 | |
| SCHEMBL8349895 | 0.81 | L3MBTL1 (0.54) | MMP1MMP9MMP13ADAM17L3MBTL1 | |
| SCHEMBL4876634 | 0.80 | SOAT1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | MMP1 3963/4885MMP9 3230/4885MMP13 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.