Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881599 | 0.91 | L3MBTL1 (0.60) | SIGMAR1L3MBTL1ALDH1A1CYP2D6TSHR | |
| SCHEMBL2701083 | 0.91 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1ALDH1A1CYP2D6TSHR | |
| SCHEMBL8349894 | 0.89 | SIGMAR1 (0.55) | SIGMAR1L3MBTL1ALDH1A1CYP2D6TSHR | |
| SCHEMBL8349895 | 0.88 | L3MBTL1 (0.54) | SIGMAR1L3MBTL1ALDH1A1CYP2D6TSHR | |
| SCHEMBL4883886 | 0.85 | L3MBTL1 (0.54) | SIGMAR1L3MBTL1ALDH1A1CYP2D6TSHR | |
| SCHEMBL4883883 | 0.85 | MMP1 (0.52) | SIGMAR1L3MBTL1ALDH1A1HTTFAAH | |
| SCHEMBL4816046 | 0.84 | ALDH1A1 (0.80) | SIGMAR1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2794291 | 0.83 | OPRL1 (0.64) | SIGMAR1ALDH1A1CYP2D6TSHRLMNA | |
| Hydrochloric Acid SCHEMBL6288091 | 0.83 | ALDH1A1 (0.78) | SIGMAR1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4872645 | 0.82 | OPRD1 (0.56) | L3MBTL1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | SIGMAR1 298/4885L3MBTL1 3484/4885ALDH1A1 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.