Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618496 | 0.82 | LTA4H (0.53) | CSNK2A1LTA4HMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27569179 | 0.82 | MRGPRX4 (0.51) | CSNK2A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4057023 | 0.77 | CHRNA7 (0.65) | LTA4HSMN1; SMN2CYP1A2CYP2C19CHRNB2 | |
| SCHEMBL8958913 | 0.76 | LTA4H (0.63) | CSNK2A1LTA4HMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5570353 | 0.76 | BCHE (0.51) | MEN1KMT2ANPSR1 | |
| SCHEMBL4904834 | 0.76 | MEN1 (0.47) | CSNK2A1MEN1KMT2ANPSR1 | |
| SCHEMBL17658995 | 0.76 | ALOX5 (0.58) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5569180 | 0.76 | ALOX5 (0.46) | CSNK2A1LTA4HSMN1; SMN2 | |
| SCHEMBL10599543 | 0.75 | LMNA (0.69) | LTA4HSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11856925 | 0.75 | LMNA (0.69) | LTA4HSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |