SCHEMBL48845

SCHEMBL48845

CN(C)C=Nc1ccncc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
CHRM5 P08912 1/20 0.46
CHKA P35790 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 4/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
ALOX15 P16050 3/20 0.41
MEN1 O00255 3/20 0.41
CASP1 P29466 2/20 0.41
HBB P68871 1/20 0.41
KDM4E B2RXH2 6/20 0.39
ALDH1A1 P00352 6/20 0.39
GAA P10253 4/20 0.39
TP53 P04637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48844 1.00 KMT2A (0.47) KMT2ACHRM5CHKASMN1; SMN2MAPT
SCHEMBL17761949 0.76 ALDH1A1 (0.53) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL218111 0.76 ALDH1A1 (0.53) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL218110 0.76 ALDH1A1 (0.53) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL17828618 0.74 ALDH1A1 (0.55) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11666035 0.73 S100B (0.62) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11209775 0.73 KMT2A (0.47) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11209773 0.73 KMT2A (0.47) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL6662201 0.73 S100B (0.62) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL6659427 0.73 S100B (0.62) KMT2ASMN1; SMN2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129136-B2 Kit for performing an assay CYANAGEN SRL (IT) 2012-03-06 US claimed
EP-1962095-B1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-06-15 EP claimed
US-20110053200-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-03-03 US claimed
US-7803573-B2 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2010-09-28 US claimed
US-20080241868-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2008-10-02 US claimed
EP-1962095-A1 Method for increasing light emission from a chemiluminescent reaction Cyanagen Srl (IT) 2008-08-27 EP claimed
US-8129136-B2 Kit for performing an assay CYANAGEN SRL (IT) 2012-03-06 US disclosed
EP-1962095-B1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-06-15 EP disclosed
US-20110053200-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2011-03-03 US disclosed
US-7803573-B2 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2010-09-28 US disclosed
US-20080241868-A1 Method for increasing light emission from a chemiluminescent reaction CYANAGEN SRL (IT) 2008-10-02 US disclosed
EP-1962095-A1 Method for increasing light emission from a chemiluminescent reaction Cyanagen Srl (IT) 2008-08-27 EP disclosed