Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209773 | 1.00 | KMT2A (0.47) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL218110 | 0.76 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL218111 | 0.76 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL17761949 | 0.76 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL17828618 | 0.74 | ALDH1A1 (0.55) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL6662201 | 0.73 | S100B (0.62) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL48845 | 0.73 | KMT2A (0.47) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL48844 | 0.73 | KMT2A (0.47) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL6659427 | 0.73 | S100B (0.62) | KMT2AALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL10342089 | 0.71 | KMT2A (0.50) | KMT2AALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259504-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | claimed |
| US-20210147371-A1 | OXADIAZOLINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | US | disclosed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147371-A1 | OXADIAZOLINE DERIVATIVES | DDT, FOXO3, PDCD4 | KMT2A 3107/4885ALDH1A1 1210/4885KDM4E 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.