SCHEMBL4885673

SCHEMBL4885673

O=Cc1ccc(Nc2cc(C=O)ccc2-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
CYP2A6 P11509 1/20 0.41
NR4A1 P22736 1/20 0.40
GAA P10253 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
EGFR P00533 2/20 0.37
MAPT P10636 2/20 0.37
RGS12 O14924 1/20 0.37
GMNN O75496 1/20 0.37
PRKD3 O94806 1/20 0.37
LMNA P02545 1/20 0.37
PRKCG P05129 1/20 0.37
PRKCB P05771 1/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25125805 0.80 ALDH1A1 (0.48) ALDH1A1CYP2A6NR4A1GAAKDM4E
SCHEMBL6990239 0.80 ALDH1A1 (0.42) ALDH1A1CYP2A6KDM4EMEN1KMT2A
SCHEMBL9453796 0.79 L3MBTL1 (0.41) ALDH1A1NR4A1KDM4ENPSR1MAPK14
Biphenyl SCHEMBL10588601 0.78 L3MBTL1 (0.40) NR4A1KDM4EMEN1KMT2ANPSR1
SCHEMBL6995100 0.76 ALDH1A1 (0.42) ALDH1A1CYP2A6KDM4EMEN1KMT2A
SCHEMBL5490742 0.75 ALDH1A1 (0.50) ALDH1A1CYP2A6KDM4EMEN1KMT2A
SCHEMBL29671482 0.75 ALDH1A1 (0.50) ALDH1A1CYP2A6KDM4EMEN1KMT2A
SCHEMBL17547153 0.75 ALK (0.46) ALDH1A1GAAKDM4EMEN1KMT2A
SCHEMBL16858258 0.75 ALK (0.46) ALDH1A1GAAKDM4EMEN1KMT2A
SCHEMBL25126214 0.75 DRD1 (0.47) ALDH1A1NR4A1MEN1KMT2AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7432028-B2 Polymeric charge transport compositions SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-07 US disclosed
EP-1471391-B1 Polymeric charge transport compositions SAMSUNG ELECTRONICS CO LTD (KR) 2006-01-25 EP disclosed
EP-1471391-A1 Polymeric charge transport compositions Samsung Electronics Co., Ltd. (KR) 2004-10-27 EP disclosed
US-20040191655-A1 Polymeric charge transport compositions S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-30 US disclosed