Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885965 | 1.00 | LMNA (0.54) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4885748 | 0.91 | P2RX1 (0.48) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4885991 | 0.90 | KCNK3 (0.47) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4885989 | 0.90 | KCNK3 (0.47) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4883201 | 0.88 | RAB9A (0.49) | LMNAKMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4883196 | 0.88 | RAB9A (0.49) | LMNAKMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4877981 | 0.88 | MAPT (0.48) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4882188 | 0.88 | MAPT (0.48) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4877985 | 0.88 | MAPT (0.48) | LMNAKMT2AKDM4EPOLBPTBP1 | |
| SCHEMBL4882184 | 0.88 | MAPT (0.48) | LMNAKMT2AKDM4EPOLBPTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | LMNA 2096/4885KMT2A 3684/4885KDM4E 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.