Benzimidazole

Benzimidazole

SCHEMBL4886532

c1ccc2[nH]cnc2c1.c1ccc2[nH]nnc2c1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.39
PDPK1 O15530 1/20 0.39
CA12 O43570 1/20 0.39
PARP1 P09874 1/20 0.39
ALOX15 P16050 1/20 0.39
CA9 Q16790 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
PRKCI P41743 1/20 0.39
KDM4E B2RXH2 5/20 0.38
QPCTL Q9NXS2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
QPCT Q16769 4/20 0.38
HPGD P15428 3/20 0.38
RAB9A P51151 2/20 0.38
HTT P42858 1/20 0.38
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
MAPT P10636 1/20 0.38
RAD52 P43351 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL3825981 0.84 KDM4E (0.33) SMN1; SMN2KDM4EQPCTLALDH1A1QPCT
Benzimidazole SCHEMBL29408372 0.84
Benzimidazole SCHEMBL461969 0.84 SMN1; SMN2 (0.50) SMN1; SMN2PDPK1CA12PARP1ALOX15
Benzimidazole SCHEMBL29358377 0.84
Benzimidazole SCHEMBL6009 0.84
Benzimidazole SCHEMBL10931770 0.84 SMN1; SMN2 (0.50) SMN1; SMN2PDPK1CA12PARP1ALOX15
Benzotriazole SCHEMBL29381270 0.84
Benzotriazole SCHEMBL6088869 0.84 ALDH1A1 (0.41) SMN1; SMN2PDPK1KDM4EALDH1A1RAB9A
Benzotriazole SCHEMBL8956 0.84
Benzimidazole SCHEMBL23673327 0.82 SMN1; SMN2 (0.48) SMN1; SMN2PDPK1CA12PARP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133776-A Coating composition and product containing coating formed by coating composition 广东华润涂料有限公司 2022-03-04 CN disclosed
CN-114075333-A Modified polycarbodiimide compound, coating composition, and coated article 广东华润涂料有限公司 2022-02-22 CN disclosed
CN-114075398-A Coating composition and coated article including coating layer formed by coating composition 广东华润涂料有限公司 2022-02-22 CN disclosed
CN-107614497-B Corrosion inhibitors 艺康美国股份有限公司 2021-08-03 CN disclosed
US-10190222-B2 Corrosion inhibitors ECOLAB USA INC. (US) 2019-01-29 US disclosed
EP-3303324-A2 NOVEL CORROSION INHIBITORS Ecolab USA Inc. (US) 2018-04-11 EP disclosed
US-20160348251-A1 Novel Corrosion Inhibitors ECOLAB USA INC. (US) 2016-12-01 US disclosed
WO-2016191667-A2 NOVEL CORROSION INHIBITORS ECOLAB USA INC. (US) 2016-12-01 WO disclosed
CN-105820156-A Benzotriazole benzimidazoline as well as preparation method and application thereof 广东工业大学 2016-08-03 CN disclosed
CN-105820156-A Benzotriazole benzimidazoline as well as preparation method and application thereof 广东工业大学 2016-08-03 CN disclosed
EP-2747159-A1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR MANUFACTURING SAME JX Nippon Oil & Energy Corporation (JP) 2014-06-25 EP disclosed
US-20140150868-A1 PHOTOELECTRIC CONVERSION ELEMENT AND MANUFACTURING METHOD THEREOF JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-06-05 US disclosed
US-20080274620-A1 CHEMICAL MECHANICAL POLISHING AGENT KIT AND CHEMICAL MECHANICAL POLISHING METHOD USING THE SAME JSR CORPORATION (JP) 2008-11-06 US disclosed
US-4735894-A PROJECTION JOINED CRYSTALS OF DIFFERENT HALOGEN COMPOSITIONS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-05 US disclosed
EP-0040842-B1 LAMINATING PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-15 EP disclosed
EP-0044059-A1 Process for the dyeing in a gel state of fibrous articles of wet-spun acrylonitrile polymers HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-20 EP disclosed
EP-0044061-A1 Process for the dyeing in a gel state of fibrous articles spun from acrylonitrile polymer solutions in organic solvents HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-20 EP disclosed
EP-0044062-A1 Process for the dyeing in a gel state of fibrous articles of dry spun acrylonitrile polymers HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-20 EP disclosed
US-4071527-A Certain benzothiazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160348251-A1 Novel Corrosion Inhibitors CAT, BLVRB, SOD1 SMN1; SMN2 4743/4885PDPK1 4489/4885CA12 137/4885
US-10190222-B2 Corrosion inhibitors CAT, BLVRB, CBR3 SMN1; SMN2 4706/4885PDPK1 4415/4885CA12 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.