Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888221 | 0.89 | MEN1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL4886589 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL5561106 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL6665555 | 0.78 | KMT2A (0.65) | ALDH1A1SMN1; SMN2RAB9ACITMAPT | |
| SCHEMBL30452307 | 0.78 | KMT2A (0.65) | ALDH1A1SMN1; SMN2RAB9ACITMAPT | |
| SCHEMBL7039856 | 0.78 | HDAC8 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9ACIT | |
| SCHEMBL5561161 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL630340 | 0.76 | NPC1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ACIT | |
| SCHEMBL14110846 | 0.76 | OPRM1 (0.54) | ALDH1A1NPC1CITMAPTMAPK1 | |
| SCHEMBL4886593 | 0.76 | ITGB1 (0.51) | ALDH1A1SMN1; SMN2CITKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-17 | — | — | US | disclosed |
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | ALDH1A1 1732/4885SMN1; SMN2 3140/4885NPC1 83/4885 |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | POLQ, POLI, POLH | ALDH1A1 2546/4885SMN1; SMN2 1943/4885NPC1 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.