Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.57 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749632 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL3219936 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL29049636 | 0.84 | XDH (0.56) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL185448 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL3705899 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL186175 | 0.80 | GABRP (0.58) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL29345465 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL5660197 | 0.80 | P4HA1 (0.56) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL4600260 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 | |
| SCHEMBL63857 | 0.80 | NAPRT (0.58) | ALDH1A1HSD17B10KDM4EALOX15HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306315-A1 | Metal-Organic Framework Catalysts and Their Use in Hydrocarbon Transformation | UNIVERSITETET I OSLO (NO) | 2008-12-11 | — | — | US | disclosed |
| EP-1909958-A2 | METAL-ORGANIC FRAMEWORK CATALYSTS AND THEIR USE IN HYDROCARBON TRANSFORMATION | Universitetet I Oslo (NO) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007007113-A2 | METAL-ORGANIC FRAMEWORK CATALYSTS AND THEIR USE IN HYDROCARBON TRANSFORMATION | UNIVERSITETET I OSLO (NO) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306315-A1 | Metal-Organic Framework Catalysts and Their Use in Hydrocarbon Transformation | POF1B, PMS2, IDH1 | ALDH1A1 1365/4885HSD17B10 1649/4885KDM4E 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.