Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CPS1 | P31327 | 10/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887092 | 0.85 | CPS1 (0.52) | ALDH1A1HPGDCPS1RAB9A | |
| SCHEMBL14087808 | 0.82 | GAA (0.48) | ALDH1A1HPGDCPS1RAB9A | |
| SCHEMBL4740737 | 0.81 | KDM4E (0.53) | ALDH1A1HPGDRAB9A | |
| SCHEMBL4889268 | 0.81 | LMNA (0.47) | ALDH1A1RAB9A | |
| SCHEMBL4741213 | 0.81 | KDM4E (0.53) | ALDH1A1HPGDRAB9A | |
| SCHEMBL4787091 | 0.77 | PLA2G1B (0.55) | ALDH1A1HPGDRAB9A | |
| SCHEMBL14314760 | 0.77 | CHRNB2 (0.65) | ALDH1A1HPGD | |
| SCHEMBL15650053 | 0.76 | ALDH1A1 (0.53) | ALDH1A1RAB9A | |
| SCHEMBL29380973 | 0.74 | SMN1; SMN2 (0.59) | ALDH1A1 | |
| SCHEMBL27720018 | 0.74 | SMN1; SMN2 (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885HPGD 1356/4885CPS1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.