SCHEMBL6931652

SCHEMBL6931652

CC(C)(C)c1ccc(Nc2ccc(CCc3ccccc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.51
ESRRG P62508 2/20 0.51
NPC1 O15118 1/20 0.51
NR1H4 Q96RI1 3/20 0.48
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
CYP2C19 P33261 1/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
FLT1 P17948 1/20 0.43
KDR P35968 1/20 0.43
KCNH2 Q12809 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547537 0.88 RAB9A (0.56) RAB9AESRRGNPC1LMNAPOLB
Diphenylamine SCHEMBL29287150 0.84 ALDH1A1 (0.62) RAB9ALMNAPOLBGAACYP2C19
SCHEMBL502030 0.84 ALDH1A1 (0.62) RAB9ALMNAPOLBGAACYP2C19
SCHEMBL2355458 0.84 ALDH1A1 (0.60) RAB9ANPC1LMNAGAACYP2C19
SCHEMBL6932079 0.82 ALDH1A1 (0.65) LMNAGAACYP2C19SIRT2ALDH1A1
SCHEMBL18403272 0.80 FLT1 (0.42) RAB9AESRRGNPC1NR1H4LMNA
SCHEMBL3022509 0.80 KCNH2 (0.58) RAB9AESRRGNPC1NR1H4LMNA
SCHEMBL7652240 0.80 HPGD (0.50) RAB9AESRRGNPC1NR1H4LMNA
SCHEMBL13167599 0.80 L3MBTL1 (0.63) RAB9AESRRGNPC1NR1H4LMNA
Diphenylamine SCHEMBL9561449 0.80 HSD17B10 (0.63) LMNAGAACYP2C19SIRT2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023377-B1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEM CO INC (US) 2003-12-03 EP claimed
US-6348514-B1 ISOCYANATE REACTIVE COMPOSITION WITH STABILIZER OF METHYL 3-(4-HYDROXY-3,5-DI-TERT-BUTYLPHENYL)PROPIONATE UNIROYAL CHEMICAL COMPANY, INC. 2002-02-19 US claimed
EP-1023377-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 2000-08-02 EP claimed
WO-1999016821-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
US-5571453-A PHOTOSTABILITY USING REACTION PRODUCT OF DIPHENYLAMINE, ISOBUTYLENE AND DIISOBUTYLENE AND STERICALLY HINDERED PHENOL AND TRIHYDROCARBYL PHOSPHITE UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-05 US disclosed
WO-1996012760-A2 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-05-02 WO disclosed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP disclosed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO disclosed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US disclosed
EP-0399142-B1 Stabilizer compositions for polyols and polyurethane foam VANDERBILT CO R T (US) 1994-01-26 EP disclosed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US disclosed
EP-0556612-A1 Synergistic stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1993-08-25 EP disclosed
US-5156762-A 2,6-Di-tert-butyl-4-sec-butylphenol, phenothiazine or alkyl-substitued derivative, and reaction product of styrene, diisobutylene and diphenylamine R. T. VANDERBILT COMPANY, INC. (US) 1992-10-20 US disclosed
US-5143943-A 2,6-di-tert-butyl-4-sec-butylphenol; reaction product of styrene, diphenylamine, and diisobutylene; and phenothiazine compound; discoloration inhibition R. T. VANDERBILT COMPANY, INC. (US) 1992-09-01 US disclosed
EP-0399142-A2 Stabilizer compositions for polyols and polyurethane foam R.T. VANDERBILT COMPANY, INC. (US) 1990-11-28 EP disclosed
US-4933374-A 2,6-DI-TERT-BUTYL-4-SEC-BUTYLPHENOL, REACTION PRODUCT OF DIISOBUTYLENE, STYRENE AND DIPHENYLAMINE R. T. VANDERBILT COMPANY, INC. (US) 1990-06-12 US disclosed