Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4887981

COc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1OCc1ccccc1.[Cl-]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
HSD17B10 Q99714 1/20 0.53
ABCB1 P08183 2/20 0.51
ABCG2 Q9UNQ0 1/20 0.51
KDM4E B2RXH2 4/20 0.51
LMNA P02545 4/20 0.51
HTT P42858 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KMT2A Q03164 2/20 0.51
NPY1R P25929 1/20 0.51
NPY2R P49146 1/20 0.51
BCHE P06276 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
BLM P54132 1/20 0.50
TSHR P16473 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10424163 0.88 LDHA (0.53) ABCB1ABCG2KDM4ELMNASMN1; SMN2
SCHEMBL30596298 0.87 LDHA (0.54) ABCB1ABCG2KDM4ELMNASMN1; SMN2
Bromide SCHEMBL29880790 0.85 LDHA (0.53) ABCB1ABCG2KDM4ELMNASMN1; SMN2
Bromide SCHEMBL4260842 0.85 LDHA (0.53) ABCB1ABCG2KDM4ELMNASMN1; SMN2
Hydrochloric Acid SCHEMBL3536559 0.80 KDM1A (0.45) SMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL8554822 0.79 MAPK1 (0.64) MAPK1HSD17B10ABCB1ABCG2KDM4E
SCHEMBL3058722 0.79 SIGMAR1 (0.57) MAPK1HSD17B10KDM4ELMNAHTT
Hydrochloric Acid SCHEMBL81008 0.78 RXRA (0.47)
Hydrochloric Acid SCHEMBL5417557 0.78 KDM1A (0.46) MAPK1HSD17B10LMNAHTTSMN1; SMN2
SCHEMBL2060386 0.78 MAPK1 (0.63) MAPK1HSD17B10ABCB1ABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP claimed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US claimed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO claimed
US-20150201622-A1 NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF CTT GROUP INC (CA) 2015-07-23 US disclosed
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP disclosed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US disclosed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO disclosed