SCHEMBL48890

SCHEMBL48890

CC(C)(C)C(=O)OC1CNC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 4/20 0.32
CHRNA4 P43681 4/20 0.32
CHRNB4 P30926 3/20 0.32
CHRNA3 P32297 3/20 0.32
CHRNA7 P36544 1/20 0.32
ATM Q13315 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL48285 0.98 CHRNB2 (0.31) CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7
SCHEMBL20617836 0.84 SLC6A1 (0.33) CYP19A1
SCHEMBL27598186 0.84 SLC6A1 (0.33) CYP19A1
SCHEMBL27653752 0.84 SLC6A1 (0.33) CYP19A1
SCHEMBL27504346 0.81 SLC6A1 (0.40) CHRNB2CHRNA4ATMCYP19A1
SCHEMBL27744409 0.81 SLC6A1 (0.40) CHRNB2CHRNA4ATMCYP19A1
SCHEMBL27657052 0.81 SLC6A1 (0.40) CHRNB2CHRNA4ATMCYP19A1
SCHEMBL27908028 0.79 CYP19A1 (0.38) ATMCYP19A1
SCHEMBL914574 0.78 CHRM3 (0.39) CYP19A1
SCHEMBL17886845 0.78 CYP19A1 (0.41) ATMCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626888-A1 COMPOUNDS Redx Pharma Limited (GB) 2025-10-08 EP disclosed
WO-2024115890-A1 COMPOUNDS REDX PHARMA PLC (GB) 2024-06-06 WO disclosed
CN-110461326-A Novel substituted N' -hydroxycarbamimidoyl-1, 2, 5-oxadiazole compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors MERCK SHARP & DOHME 2019-11-15 CN disclosed
CN-106061963-B Heterocyclic modulators of lipid synthesis and combinations thereof 3-V生物科学股份有限公司 2019-10-22 CN disclosed
CN-110167934-A Monocycle and spiro-compound containing cyclobutane and containing azetidine as α V integrin inhibitor 百时美施贵宝公司 2019-08-23 CN disclosed
CN-110041250-A The benzene compound being substituted EPIZYME股份有限公司 2019-07-23 CN disclosed
CN-109963834-A It can be used as the novel azetidine derivatives of cortex catecholaminergic modulators of neurotransmission 综合研究实验室瑞典股份公司 2019-07-02 CN disclosed
CN-109843888-A 6, 7, 8, 9-tetrahydro-3H-pyrazolo [4, 3-f ] isoquinoline derivatives useful for the treatment of cancer 阿斯利康(瑞典)有限公司 2019-06-04 CN disclosed
CN-109776523-A Heterocyclic compound and application thereof in medicine 杭州安霖药业有限公司 2019-05-21 CN disclosed
CN-109328187-A A kind of new compound and its preparation and application with FGFR inhibitory activity 中国科学院上海药物研究所 2019-02-12 CN disclosed
CN-101903380-A Amino cyclohexyl methyl-oxazoles of 5-pyridine-2-ketone derivatives ACTELION PHARMACEUTICALS LTD 2010-12-01 CN disclosed
CN-101678020-A Quinoxaline derivatives as inhibitors of the tyrosine kinase activity of Janus kinases NOVARTIS AG 2010-03-24 CN disclosed
CN-101679351-A Quinoline compounds suitable for treating didorders that respond to modulation of the serotonin 5-ht6 receptor ABBOTT GMBH & CO KG 2010-03-24 CN disclosed
CN-101506140-A Cyclic 11 beta-hydroxysteroid dehydrogenase type I inhibitors BRISTOL MYERS SQUIBB CO (US) 2009-08-12 CN disclosed
CN-101479255-A c-MET protein kinase inhibitors for the treatment of proliferative disorders VERTEX PHARMA (US) 2009-07-08 CN disclosed
CN-101454328-A Novel mch receptor antagonists LILLY CO ELI (US) 2009-06-10 CN disclosed
US-20090111992-A1 ALKYL ETHER DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-30 US disclosed
US-7468443-B2 Alkyl ether derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2008-12-23 US disclosed
CN-101137628-A Non-anilinic derivatives of isothiazol-3(2h)-one 1,1-dioxides as liver x receptor modulators ASTRAZENECA AB (SE) 2008-03-05 CN disclosed
CN-101018773-A Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes ASTRAZENECA AB (SE) 2007-08-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111992-A1 ALKYL ETHER DERIVATIVES OR SALTS THEREOF AHNAK, NGF, PMP22 CHRNB2 232/4885CHRNA4 251/4885CHRNB4 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.