Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331831 | 0.82 | ALDH1A1 (0.44) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL4889248 | 0.81 | CNR2 (0.34) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL332587 | 0.76 | LMNA (0.33) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL331523 | 0.74 | MAPT (0.34) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL331385 | 0.72 | NR3C1 (0.39) | NR3C1NR3C2 | |
| SCHEMBL332047 | 0.69 | ALDH1A1 (0.39) | TSHRHTR2AALDH1A1MAPTLMNA | |
| SCHEMBL3530718 | 0.68 | ALDH1A1 (0.45) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL331835 | 0.68 | ALDH1A1 (0.45) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3529914 | 0.66 | ALDH1A1 (0.41) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL331531 | 0.65 | ALDH1A1 (0.33) | ALDH1A1NR3C1NR3C2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153859-A1 | MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | REHWINKEL HARTMUT | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153859-A1 | MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | DHPS, TNF, IL1B | ABCB11 1394/4885CYP1A2 47/4885CYP3A4 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.