Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479127 | 0.97 | CTSS (0.49) | CTSBCTSSCTSKITGB3ITGAV | |
| SCHEMBL1023687 | 0.94 | TACR1 (0.47) | CTSBCTSSCTSKSCN9ATACR1 | |
| SCHEMBL4847576 | 0.94 | TACR1 (0.47) | CTSBCTSSCTSKSCN9ATACR1 | |
| SCHEMBL14497710 | 0.91 | CTSS (0.46) | CTSBCTSSCTSKPTPN1TACR1 | |
| SCHEMBL13479136 | 0.90 | CTSS (0.42) | CTSBCTSSCTSKITGB3PTPN1 | |
| SCHEMBL13479128 | 0.90 | TACR1 (0.46) | CTSBCTSSCTSKSCN9ATACR1 | |
| SCHEMBL5063469 | 0.90 | CTSB (0.42) | CTSBCTSSCTSKITGB3ITGAV | |
| SCHEMBL13479129 | 0.89 | TACR1 (0.43) | CTSBCTSSCTSKSCN9ATACR1 | |
| SCHEMBL13479135 | 0.89 | TACR1 (0.43) | CTSBCTSSCTSKPTPN1SCN9A | |
| SCHEMBL14497714 | 0.89 | CTSS (0.45) | CTSBCTSSCTSKPTPN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | ARG1, HRH3, H1-0 | CTSB 1334/4885CTSS 1049/4885CTSK 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.