Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239642 | 0.82 | ALOX5 (0.70) | HDAC6ALOX5EPHX2MAPTNPC1 | |
| SCHEMBL14111113 | 0.81 | LTA4H (0.66) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4600092 | 0.81 | LTA4H (0.67) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4598883 | 0.81 | LTA4H (0.67) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4599431 | 0.81 | LTA4H (0.67) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4598874 | 0.80 | LTA4H (0.66) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4598882 | 0.80 | LTA4H (0.66) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4599698 | 0.78 | LTA4H (0.62) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4599694 | 0.78 | LTA4H (0.62) | LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4600154 | 0.78 | LTA4H (0.62) | LTA4HNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-17 | — | — | US | disclosed |
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | HDAC1 1003/4885HDAC6 592/4885HDAC3 328/4885 |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | POLQ, POLI, POLH | HDAC1 1454/4885HDAC6 1578/4885HDAC3 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.