Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7164899 | 0.74 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL816978 | 0.73 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL29695725 | 0.73 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL4475529 | 0.71 | PNMT (0.33) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL4475731 | 0.71 | PNMT (0.33) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL4890367 | 0.71 | BCHE (0.30) | — | |
| SCHEMBL14735872 | 0.70 | PNMT (0.34) | PNMTNPC1RAB9A | |
| SCHEMBL14735870 | 0.70 | PNMT (0.34) | PNMTNPC1RAB9A | |
| SCHEMBL8379134 | 0.70 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL4466187 | 0.70 | PNMT (0.33) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8373011-B2 | Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability | IDEMITSU KOSAN CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| US-20080146469-A1 | Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition | IDEMITSU KOSAN CO., LTD. (JP) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146469-A1 | Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition | ALOX15, ALOX12, ALOX15B | PNMT 3641/4885DRD2 318/4885DRD4 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.