Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26262574 | 0.83 | ACP1 (0.48) | ACP1PDK2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL26262323 | 0.80 | ACP1 (0.46) | ACP1CYP1A2CYP3A4MAPK1TSHR | |
| SCHEMBL13990192 | 0.79 | TSHR (0.48) | ACP1PDK2CYP3A4MAPK1TSHR | |
| SCHEMBL27014441 | 0.75 | ACP1 (0.44) | ACP1CYP1A2CYP3A4MAPK1TSHR | |
| SCHEMBL31049801 | 0.75 | ALDH1A1 (0.42) | PDK2MAPK1TSHRALOX15HSD17B10 | |
| SCHEMBL31049803 | 0.75 | ALDH1A1 (0.42) | PDK2MAPK1TSHRALOX15HSD17B10 | |
| SCHEMBL27015662 | 0.74 | ACP1 (0.41) | ACP1CYP1A2CYP3A4MAPK1TSHR | |
| SCHEMBL27014476 | 0.73 | ACP1 (0.43) | ACP1CYP1A2CYP3A4MAPK1TSHR | |
| SCHEMBL197671 | 0.72 | HSD11B1 (0.56) | CYP1A2CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL18000078 | 0.71 | CRHR1 (0.43) | PDK2TSHRALOX15HSD17B10JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944723-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9522967-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY INTERNATIONAL INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160228334-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS FEATURING NOVEL AMINE ACCELERATOR FOR IMPROVED COLOR STABILITY AND REDUCED POLYMERIZATION STRESS THEREBY | DENTSPLY SIRONA INC. | 2016-08-11 | — | — | US | disclosed |
| US-20080306179-A1 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228334-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS FEATURING NOVEL AMINE ACCELERATOR FOR IMPROVED COLOR STABILITY AND REDUCED POLYMERIZATION STRESS THEREBY | RAD51, PNMT, FANCD2 | ACP1 2448/4885PDK2 2573/4885CYP1A2 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.