Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 15/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888522 | 0.91 | VDR (0.59) | VDRRORCPGRRORANR1H4 | |
| SCHEMBL4884684 | 0.89 | VDR (0.55) | VDRRORCPGRRORANR1H4 | |
| SCHEMBL4894502 | 0.88 | VDR (0.67) | VDR | |
| SCHEMBL4886580 | 0.88 | VDR (0.63) | VDRRORCPGRNR1H2NR1H3 | |
| SCHEMBL4884277 | 0.81 | VDR (0.79) | VDRRORCPGRNR1H2NR1H3 | |
| SCHEMBL4887639 | 0.80 | VDR (0.52) | VDRPGRNR1H2NR1H3 | |
| SCHEMBL4884687 | 0.80 | VDR (0.52) | VDRRORCPGRNR1H2NR1H3 | |
| SCHEMBL2639809 | 0.80 | VDR (0.77) | VDRRORCPGRNR1H2NR1H3 | |
| SCHEMBL4884826 | 0.80 | VDR (0.76) | VDR | |
| SCHEMBL6576788 | 0.79 | VDR (0.76) | VDRRORCPGRNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194528-A1 | Pharmaceutical compositions comprising organopolysiloxane elastomers and solubilized bioactive compounds | GALDERMA RESEARCH AND DEVELOPMENT (FR) | 2008-08-14 | — | — | US | claimed |
| US-6924400-B2 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2005-08-02 | — | — | US | claimed |
| US-20080194528-A1 | Pharmaceutical compositions comprising organopolysiloxane elastomers and solubilized bioactive compounds | GALDERMA RESEARCH AND DEVELOPMENT (FR) | 2008-08-14 | — | — | US | disclosed |
| US-6924400-B2 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2005-08-02 | — | — | US | disclosed |
| US-20050004093-A1 | Beta-lactamase inhibitor prodrug | PFIZER INC | 2005-01-06 | — | — | US | disclosed |
| US-20030195259-A1 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004093-A1 | Beta-lactamase inhibitor prodrug | SI, CMBL, STS | VDR 2281/4885RORC 537/4885PGR 3553/4885 |
| US-20030195259-A1 | Triaromatic vitamin D analogues | CYP24A1, CYP2R1, VDR | VDR 3/4885RORC 93/4885PGR 409/4885 |
| US-20080194528-A1 | Pharmaceutical compositions comprising organopolysiloxane elastomers and solubilized bioactive compounds | CYP24A1, VDR, SOST | VDR 2/4885RORC 100/4885PGR 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.