Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687273 | 0.92 | ALDH1A1 (0.53) | ALDH1A1PTPN1BRD4MAPTTDP1 | |
| SCHEMBL4153190 | 0.92 | ALDH1A1 (0.47) | ALDH1A1PTPN1CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10922825 | 0.86 | ALDH1A1 (0.55) | ALDH1A1PTPN1BRD4MAPTTDP1 | |
| SCHEMBL4898090 | 0.80 | LTA4H (0.45) | MAPTTDP1L3MBTL1CYP2C19PPIA | |
| SCHEMBL10247054 | 0.77 | PTPN1 (0.55) | ALDH1A1PTPN1BRD4MAPTTDP1 | |
| SCHEMBL9740768 | 0.77 | ALDH1A1 (0.47) | ALDH1A1PTPN1BRD4MAOBLMNA | |
| SCHEMBL9654512 | 0.77 | LTA4H (0.45) | MAPTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8502633 | 0.76 | ALDH1A1 (0.49) | ALDH1A1PTPN1BRD4MAPTTDP1 | |
| SCHEMBL4890014 | 0.76 | KDM4E (0.47) | ALDH1A1BRD4PPIAHPGDSGMS2 | |
| Hydrochloric Acid SCHEMBL9683438 | 0.76 | LTA4H (0.44) | ALDH1A1MAPTTDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | BTG INTERNATIONAL LIMITED | 2008-08-21 | — | — | US | disclosed |
| WO-2006103463-A1 | IRON MODULATORS | BTG INTERNATIONAL LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |
| WO-1992013841-A1 | COMPLEXING AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498380-A1 | Complexing agents | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | SLC40A1, HAMP, FTH1 | ALDH1A1 2218/4885PTPN1 4562/4885BRD4 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.